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商品详细你好生物/喹啉酸/HB0544/1g
你好生物/喹啉酸/HB0544/1g
你好生物/喹啉酸/HB0544/1g
商品编号: HB0544-1g
品牌: hellobio
市场价: ¥624.00
美元价: 480.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product overview

  • Name
    Quinolinic acid
  • Short description
    Endogenous NMDA receptor agonist
  • Biological description
    Endogenous NMDA receptor agonist. Shows no activation at GluN1 and GluN2C subunit containing receptors. Displays neurotoxin and pro-inflammatory properties.
  • Biological action
    Agonist
  • Our products in action
    Submit Your Citation Now

Properties

  • Chemical name
    Pyridine-2,3-dicarboxylic acid
  • Molecular Weight
    167.12
  • Chemical structure
    Quinolinic acid  [89-00-9]
  • Molecular Formula
    C7H5NO4
  • CAS Number
    89-00-9

Storing and Using Your Product

  • Storage instructions
    room temperature
  • Solubility overview
    soluble in NaOH(aq) (50mM, 1eq. NaOH)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Quinolinic acid

  • Quinolinic acid, the inescapable neurotoxin.

    Guillemin GJ (2012) FEBS J 279(8) : 1356-65.
    PubMedID: 22248144
  • The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits.

    de Carvalho LP et al (1996) Neurochem Int 28(4) : 445-52.
    PubMedID: 8740453
  • Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.

    Heyes MP et al (1992) Brain 115 ( Pt 5) : 1249-73.
    PubMedID: 1422788
  • Quinolinic acid: an endogenous neurotoxin with multiple targets.

    Lugo-Huitrón R et al (2013) Oxid Med Cell Longev 2013 : 104024
    PubMedID: 24089628
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.