你好生物/喹啉酸/HB0544/1g
市场价：
¥624.00
美元价：
480.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameQuinolinic acid
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Short descriptionEndogenous NMDA receptor agonist
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Biological descriptionEndogenous NMDA receptor agonist. Shows no activation at GluN1 and GluN2C subunit containing receptors. Displays neurotoxin and pro-inflammatory properties.
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Biological actionAgonist
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Properties
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Chemical namePyridine-2,3-dicarboxylic acid
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Molecular Weight167.12
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Chemical structure
![Quinolinic acid [89-00-9]](images/hellobio/201710/hb0544.png "Quinolinic acid [89-00-9]")
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Molecular FormulaC7H5NO4
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CAS Number89-00-9
Storing and Using Your Product
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Storage instructionsroom temperature
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Solubility overviewsoluble in NaOH(aq) (50mM, 1eq. NaOH)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Quinolinic acid
Quinolinic acid, the inescapable neurotoxin.
Guillemin GJ (2012) FEBS J 279(8) : 1356-65.PubMedID: 22248144The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits.
de Carvalho LP et al (1996) Neurochem Int 28(4) : 445-52.PubMedID: 8740453Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.
Heyes MP et al (1992) Brain 115 ( Pt 5) : 1249-73.PubMedID: 1422788Quinolinic acid: an endogenous neurotoxin with multiple targets.
Lugo-Huitrón R et al (2013) Oxid Med Cell Longev 2013 : 104024PubMedID: 24089628
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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