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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > Hello Bio/Prostaglandin E2/HB3460/10mg
商品详细Hello Bio/Prostaglandin E2/HB3460/10mg
Hello Bio/Prostaglandin E2/HB3460/10mg
Hello Bio/Prostaglandin E2/HB3460/10mg
商品编号: HB3460-10mg
品牌: hellobio
市场价: ¥1423.50
美元价: 1095.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product overview

  • Name
    Prostaglandin E2
  • Short description
    Endogenous prostanoid. Induces hematopoietic stem cell proliferation.
  • Biological description
    Endogenous prostanoid (Kd values are ~1-10 nM at EP1, EP2, EP3 and EP4. Shows many biological actions and modulates various pathological and physiological activities. Induces hematopoietic stem cell (HSC) proliferation.
  • Alternative names
    Dinoprostone | PGE2
  • Biological action
    Activator
  • Purity
    >98%
  • Our products in action
    Submit Your Citation Now

Properties

  • Chemical name
    (5Z,11α,13E,15S)-11,15-Dihydroxy-9-o xo-prosta-5,13-dien-1oic acid
  • Molecular Weight
    352.47
  • Chemical structure
    Prostaglandin E2 |  [363-24-6]
  • Molecular Formula
    C20H32O5
  • CAS Number
    363-24-6

Storing and Using Your Product

  • Storage instructions
    -20°C
  • Solubility overview
    soluble in DMSO (100mM) or ethanol (45mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Prostaglandin E2

  • The multiple faces of prostaglandin E2 G-protein coupled receptor signaling during the dendritic cell life cycle.

    De Keijzer et al (2013) Int J Mol Sci 14(4) : 6542-55
    PubMedID: 23528886
  • Roles of prostaglandin E2 in cardiovascular diseases.

    Suzuki et al (2011) Int Heart J 52(5) : 266-9
    PubMedID: 22008433
  • Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.

    North et al (2007) Nature 447(7147) : 1007-11
    PubMedID: 17581586
  • International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.

    Coleman et al (1994) Pharmacol Rev 46(2) : 205-29
    PubMedID: 7938166
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.