你好生物/盐酸二甲双胍/HB2153/100mg
商品编号：
HB2153-100mg
品牌：
hellobio
市场价：
¥819.00
美元价：
630.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameMetforminhydrochloride
- ShortdescriptionLKB1/AMPKactivator.Alsopromotesneurogenesis.
- BIOLOGicaldescriptionLKB1/AMPKactivator.Bloodbrainbarrierpermeable.Improvesinsulinsensitivityanddecreasesplasmaglucoselevelstoshowantidiabeticactivity.Alsoinhibitscancerstemcells(CSCs)andshowsanticancerandanti-neoplasticeffects.PromotesneurogenesisbyactivatingthePKC-CBPpathway.
- BiologicalactionActivator
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameN,N-Dimethylimidodicarbonimidicdiamidehydrochloride
- MolecularWeight165.62
- Chemicalstructure
![Metformin hydrochloride | [1115-70-4]](images/hellobio/201710/hb2153.png "Metformin hydrochloride | [1115-70-4]")
- MolecularFormulaC4H11N5.HCl
- CASNumber1115-70-4
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- Solubilityoverviewsolubleinwater(100mM)orDMSO(50mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforMetforminhydrochloride
AMP-activatedproteinkinaseinmetaboliccontrolandinsulinsignaling.
TowlerandHardie(2007)CircRes100(3):32841PubMedID:17307971Metformin,cancerandglucosemetabolism.
Salanietal(2014)EndocrRelatCancer21(6):461-71PubMedID:25273809MetforminactivatesanatypicalPKC-CBPpathwaytopromoteneurogenesisandenhancespatialmemoryformation.
Wangetal(2012)CellStemCell11(1):23-35PubMedID:22770240
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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