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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > 你好生物/盐酸异古瓦辛/HB0883/1g
商品详细你好生物/盐酸异古瓦辛/HB0883/1g
你好生物/盐酸异古瓦辛/HB0883/1g
你好生物/盐酸异古瓦辛/HB0883/1g
商品编号: HB0883-1g
品牌: hellobio
市场价: ¥17608.50
美元价: 13545.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Productoverview

  • Name
    Isoguvacinehydrochloride
  • Shortdescription
    SelectiveGABAAreceptoragoNIST
  • BIOLOGicaldescription
    SelectiveGABAAreceptoragonist(IC50=5.6µM).LesspotentthanGABA.Showsanti-epilepticactions.
  • Biologicalaction
    Agonist
  • Purity
    >99%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    1,2,3,6-Tetrahydro-4-pyridinecarboxylicacidhydrochloride
  • MolecularWeight
    163.6
  • Chemicalstructure
    Isoguvacine hydrochloride [68547-97-7]
  • MolecularFormula
    C6H9NO2.HCl
  • CASNumber
    68547-97-7
  • PubChemidentifier
    155107
  • SMILES
    C1CNCC=C1C(=O)O.Cl
  • InChi
    InChI=1S/C6H9NO2.ClH/c8-6(9)5-1-3-7-4-2-5;/h1,7H,2-4H2,(H,8,9);1H
  • InChiKey
    SUWREQRNTXCCBL-UHFFFAOYSA-N
  • MDLnumber
    MFCD00055192

StoringandUsingYourProduct

  • Storageinstructions
    Roomtemperature
  • Solubilityoverview
    Solubleinwater(100mM)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforIsoguvacinehydrochloride

  • Isoguvacinebinding,uptake,andrelease:relationtotheGABAsystem.

    WhiteWFetal(1983)JNeuRochem40(6):1701-8.
    PubMedID:6854327
  • Effectsofgamma-aminobutyricacid(GABA)agonistsandaGABAuptakeinhibitoronpharmacoresistantseizurelikeeventsinorganotypichippocampalslicecultures.

    WahabAetal(2009)EpilepsyRes86(2-3):113-23.
    PubMedID:19535226
  • Isoguvacinebinding,uptake,andrelease:relationtotheGABAsystem.

    WhiteWFetal(1983)JNeurochem40(6):1701-8.
    PubMedID:6854327
  • Understandingyourinhibitions:effectsofGABAandGABAAreceptormodulationonbraincorticalmetabolism.

    NasrallahFAetal(2009)JNeurochem108(1):57-71.
    PubMedID:19014380
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.