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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > 你好Bio/6-碘罗汉果毒素/HB1180/1mg
商品详细你好Bio/6-碘罗汉果毒素/HB1180/1mg
你好Bio/6-碘罗汉果毒素/HB1180/1mg
你好Bio/6-碘罗汉果毒素/HB1180/1mg
商品编号: HB1180
品牌: hellobio
市场价: ¥3003.00
美元价: 2310.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Productoverview

  • Name
    6"-Iodoresiniferatoxin
  • Shortdescription
    TRPV1receptorpartialagoNIST
  • BIOLOGicaldescription
    TRPV1receptorpartialagonist(Ki=0.71nMforhVR1).FullagonistatratVR1.
  • Biologicalaction
    Agonist
  • Purity
    >98%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    [(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]-4-hydroxy-2-iodo-5-methoxy-benzeneaceticacidmethylester
  • MolecularWeight
    754.6
  • MolecularFormula
    C37H39IO9
  • CASNumber
    335151-55-8

StoringandUsingYourProduct

  • Storageinstructions
    -20°C(desiccate)
  • Solubilityoverview
    solubleinethanolorDMSO
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

Referencesfor6"-Iodoresiniferatoxin

  • SynthesisandinvitroevaluationofanoveliodinatedresiniferatoxinderivativethatisanagonistatthehumanvanilloidVR1receptor.

    McDonnellMEetal(2002)BioorgMedChemLett12(8):1189-92.
    PubMedID:11934585
  • Thetamingofcapsaicin.ReversalofthevanilloidactivityofN-acylvanillaminesbyaromaticiodination.

    AppendinoGetal(2005)JMedChem48(14):4663-9.
    PubMedID:16000002
  • LowFrequencyElectroacupunctureAlleviatedSpinalNerveLigationInducedMechanicalAllodyniabyInhibitingTRPV1UpregulationinIpsilateralUndamagedDorsalRootGangliainRats.

    JiangYLetal(2013)EvidBasedComplementAlternatMed2013:170910
    PubMedID:23935654
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.