Hello Bio/20-Hydroxyecdysone/HB3718/50mg
市场价：
¥7858.50
美元价：
6045.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name20-Hydroxyecdysone
- ShortdescriptionEcdysonereceptor(EcR)agoNIST.MorepotentthanEcdysone.
- BIOLOGicaldescriptionAmemberoftheecdysteroidfamily.Ecdysonereceptor(EcR)agonist.Morepotentthanecdysone.Inducestheexpressionofgenescodingforproteinsthatthelarvarequires,anditcauseschromosomepuffs(sitesofhighexpression)toforminpolytenechromosomes.Playsakeyroleininsectdevelopment,cellproliferaton,growthandapoptosisbycontrollinggeneexpressioninvolvedinmoultingandmetamorphosis.Itactsthroughaheterodimericreceptorcomprisingtheecdysonereceptorandtheultraspiracleproteins(USP).Regulateslipolysisininsects.Appearsinmanyplantsmostlyasaprotectionagent(toxinsorantifeedants)againstherbivorousinsects.Usedforcontrolledgeneexpressioninscientificresearch,agricultureandmedicine.Usedforthedevelopmentofselectiveinsectgrowthregulatorsforuseasenvironmentallybenigninsecticides.Showsbiologicaleffectsonmammalianspecies.Neurosteroid.Antiepileptic.ActsonthemodulatorysiteoftheGABAAreceptorandpotentiatesGABAergicinhibitioninrat.Wasshowntostimulateandmodulateneutrophilproduction.Antidiabeticandantiobesity.Couldbeusedasanutritionalsupplementforthepreventionandtreatmentofobesityandobesity-associateddisorders.MayprotectPC12cellsagainstCoCl(2)-inducedcellinjurybyinhibitingROSproductionandmodulatingcomponentsofthemitochondrialapoptosispathway.Doesnothavepotentanabolicproperties,however,amuscle-specificincreaseisobservedandgenesareidentifiedtoprovideanexplanationforthemuscleaccretion.Potentialfibrosisantagonistforrenalproximaltubulecells.Actsthroughsuppressingpost-receptorsignalingofTGF-beta1andblockingtheexpressionofSnail.
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- MolecularWeight480.6
- Chemicalstructure
![20-Hydroxyecdysone [5289-74-7]](images/hellobio/201710/hb3718.png "20-Hydroxyecdysone [5289-74-7]")
- CASNumber5289-74-7
- InChiKeyNKDFYOWSKOHCCO-MQMWGCQISA-N
- AppearanceWhitesolid
StoringandUsingYourProduct
- Storageinstructions+4°C
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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