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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > Hello Bio/Forskolin/HB1348/10mg
商品详细Hello Bio/Forskolin/HB1348/10mg
Hello Bio/Forskolin/HB1348/10mg
Hello Bio/Forskolin/HB1348/10mg
商品编号: HB1348-10mg
品牌: hellobio
市场价: ¥1092.00
美元价: 840.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Product overview

  • Name
    Forskolin
  • Short description
    Cell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer.
  • Biological description
    Cell permeable, reversible adenylyl cyclase activator. Increases cAMP levels and inhibits platelet-activating factor (PAF). Also inhibits mast cell degranulation and lowers intraocular pressure. Neuronal differentiation inducer. Displays vasodilating and hypotensive properties.
  • Biological action
    Activator
  • Customer comments

    I am currently working with forskolin. The quality of product and service is very satisfying. I am very happy to have access to your high quality products. Pojeong Park, PhD student, University of Bristol, UK

  • Our products in action
    Submit Your Citation Now

Images

Properties

  • Chemical name
    [3R-(3<>H-naphtho[2,1-b]pyran-1-one
  • Molecular Weight
    410.51
  • Chemical structure
    Forskolin  [66575-29-9]
  • Molecular Formula
    C22H34O7
  • CAS Number
    66575-29-9
  • PubChem identifier
    47936
  • SMILES
    CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
  • InChi
    InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
  • InChiKey
    OHCQJHSOBUTRHG-KGGHGJDLSA-N
  • MDL number
    MFCD00082317

Storing and Using Your Product

  • Storage instructions
    -20°C (desiccate)
  • Solubility overview
    Soluble in DMSO (25 mM)
  • Important
    This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.

References for Forskolin

  • Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling.

    Insel PA et al (2003) Cell Mol Neurobiol 23(3) : 305-14.
    PubMedID: 12825829
  • Forskolin and derivatives as tools for studying the role of cAMP.

    Alasbahi RH et al (2012) Pharmazie 67(1) : 5-13.
    PubMedID: 22393824
  • Forskolin: upcoming antiglaucoma molecule.

    Wagh VD et al (2012) J Postgrad Med 58(3) : 199-202.
    PubMedID: 23023353
  • Interactions of forskolin and adenylate cyclase. Effects on substrate kinetics and protection against inactivation by heat and N-ethylmaleimide.

    Awad JA et al (1983) J Biol Chem 258(5) : 2960-5.
    PubMedID: 6681815
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.