Hello Bio/Forskolin/HB1348/10mg
商品编号:
HB1348-10mg
品牌:
hellobio
市场价:
¥1092.00
美元价:
840.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Product overview
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NameForskolin
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Short descriptionCell permeable, reversible adenylyl cyclase activator. Neuronal differentiation inducer.
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Biological descriptionCell permeable, reversible adenylyl cyclase activator. Increases cAMP levels and inhibits platelet-activating factor (PAF). Also inhibits mast cell degranulation and lowers intraocular pressure. Neuronal differentiation inducer. Displays vasodilating and hypotensive properties.
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Biological actionActivator
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Customer comments
I am currently working with forskolin. The quality of product and service is very satisfying. I am very happy to have access to your high quality products. Pojeong Park, PhD student, University of Bristol, UK
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Images
Properties
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Chemical name[3R-(3<>H-naphtho[2,1-b]pyran-1-one
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Molecular Weight410.51
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Chemical structure
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Molecular FormulaC22H34O7
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CAS Number66575-29-9
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PubChem identifier47936
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SMILESCC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
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InChiInChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
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InChiKeyOHCQJHSOBUTRHG-KGGHGJDLSA-N
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MDL numberMFCD00082317
Storing and Using Your Product
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Storage instructions-20°C (desiccate)
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Solubility overviewSoluble in DMSO (25 mM)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for Forskolin
Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling.
Insel PA et al (2003) Cell Mol Neurobiol 23(3) : 305-14.PubMedID: 12825829Forskolin and derivatives as tools for studying the role of cAMP.
Alasbahi RH et al (2012) Pharmazie 67(1) : 5-13.PubMedID: 22393824Forskolin: upcoming antiglaucoma molecule.
Wagh VD et al (2012) J Postgrad Med 58(3) : 199-202.PubMedID: 23023353Interactions of forskolin and adenylate cyclase. Effects on substrate kinetics and protection against inactivation by heat and N-ethylmaleimide.
Awad JA et al (1983) J Biol Chem 258(5) : 2960-5.PubMedID: 6681815
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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