Hello Bio/Fluticasone propionate/HB1091/100mg
商品编号：
HB1091-100mg
品牌：
hellobio
市场价：
¥13611.00
美元价：
10470.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameFluticasonepropionate
- ShortdescriptionSelectiveglucocorticoidreceptoragoNIST
- BIOLOGicaldescriptionSelectiveglucocorticoidreceptoragonist(Kd=0.5nM).Reducesexpressionofmastcells,suppressesmastcelldegranulation,enhanceseosinophilapoptosisandinhibitsTcellproliferation.PotentiatesKv1channelcurrent(EC50=37nM).Showsanti-inflammatoryandanti-allergyactions.
- BiologicalactionAgonist
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioicacidfluoromethylester
- MolecularWeight500.57
- Chemicalstructure
![Fluticasone propionate [80474-14-2]](images/hellobio/201710/hb1091.png "Fluticasone propionate [80474-14-2]")
- MolecularFormulaC25H31F3O5S
- CASNumber80474-14-2
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(50mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforFluticasonepropionate
Theanti-inflammatoryprofileoffluticasonepropionate.
JohnsonM(1995)Allergy50(23Suppl):11-4.PubMedID:7604948Basicresearchonvirus-inducedasthmaexacerbation:inhibitionofinflammatorychemokineexpressionbyfluticasonepropionate.
MatsukuraSetal(2013)IntArchAllergyImmunol161Suppl2:84-92.PubMedID:23711858PotentiationoftheKv1familyK(+)channelbycortisoneanalogues.
PanYetal(2012)ACSChemBiol7(10):1641-6.PubMedID:22803826Enhancementofhumaneosinophilapoptosisbyfluticasonepropionate,budesonide,andbeclomethasone.
ZhangXetal(2000)EurJPharmacol406(3):325-32.PubMedID:11040338
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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