Hello Bio/Endomorphin-1/HB2410/5mg
商品编号：
HB2410-5mg
品牌：
hellobio
市场价：
¥916.50
美元价：
705.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameEndomorphin-1
- ShortdescriptionPotent,selectiveμ-opioidreceptoragoNIST
- BIOLOGicaldescriptionPotent,selectiveμ-opioidreceptoragonist(Kivaluesare360pMand>1000nMatμ,δandκreceptorsrespectively).Endogenouspeptide.Shows>4000and15,000-foldselectivityforμoverδandκreceptors.Showsantinociceptiveactivity.
- BiologicalactionAgonist
- OurproductsinactionSubmitYourCitationNow
Properties
- ChemicalnameTyr-Pro-Trp-Phe-NH2
- MolecularWeight610.67
- MolecularFormulaC34H38N6O5
- CASNumber189388-22-5
- PubChemidentifier5311080
- SMILESC1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)N
- InChiKeyZEXLJFNSKAHNFH-SYKYGTKKSA-N
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- Solubilityoverviewsolubleinwater
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforEndomorphin-1
Apotentandselectiveendogenousagonistforthemu-opiatereceptor.
ZADInaetal(1997)Nature386:499-502PubMedID:9087409OppositeeffectsofneuropeptideFFoncentralantinociceptioninducedbyendomorphin-1andendomorphin-2inmice.
Wangetal(2014)PLoS9:e103773PubMedID:25090615Endomorphin-1andendomorphin-2:pharmacologyoftheselectiveendogenousmu-opioidreceptoragonists.
Horvath(2000)PharmacolTher88:437-63PubMedID:11337033
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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