Hello Bio/(R,S)-3,5-DHPG/HB0026/10mg
商品编号:
HB0026-10mg
品牌:
hellobio
市场价:
¥1092.00
美元价:
840.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Productoverview
- Name(R,S)-3,5-DHPG
- ShortdescriptionSelectivegroupI(mGluR1/mGluR5)agoNIST
- BIOLOGicaldescriptionSelectivegroupImGluR(mGluR1/mGluR5)agonist.StimulatesPLCandinhibitsPLDresponse.InducesLTDinthehippocampus.
- Alternativenames(RS)-3,5-Dihydroxyphenylglycine
- BiologicalactionAgonist
- Purity>99%
- Customercomments
GettingonwellwithDHPG&picrotoxin–theydowhatthey’resupposedto!ProfessorBrunoFrenguelli,UniversityofWarwick,UK
- Ourproductsinaction1citationSubmitYourCitationNow
Images
Properties
- Chemicalname(RS)-3,5-Dihydroxyphenylglycine
- MolecularWeight183.16
- Chemicalstructure
- MolecularFormulaC8H9NO4
- CASNumber19641-83-9
- PubChemidentifier108001
- SMILESC1=C(C=C(C=C1O)O)C(C(=O)O)N
- SourceSynthetic
- InChiInChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)
- InChiKeyHOOWCUZPEFNHDT-UHFFFAOYSA-N
- AppearanceWhitesolid
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- SolubilityoverviewSolubleinwater(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(R,S)-3,5-DHPG
PharmacologicalcharacterizationofmetabotropicglutamatereceptorscoupledtophospholipaseDintherathippocampus.
Pellegrini-GiampietroDEetal(1996)BrJPharmacol118(4):1035-43.PubMedID:8799579ThegroupImGlureceptoragonistDHPGinducesanovelformofLTDintheCA1regionofthehippocampus.
PalmerMJetal(1997)Neuropharmacology36(11-12):1517-32.PubMedID:9517422InteractionofDHPG-LTDandsynaptic-LTDatsenescentCA3-CA1hippocampalsynapses.
KumarAetal(2014)Hippocampus24(4):466-75.PubMedID:24390964
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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