Hello Bio/Dexamethasone/HB2521/
市场价：
¥585.00
美元价：
450.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameDexamethasone
- ShortdescriptionSyntheticglucocorticoid.InduceshMSCdifferentiation.
- BIOLOGicaldescription
Syntheticglucocorticoid. Differentiatesmesenchymalstemcells(MSCs)intoADIpogenic,chondrogenicandosteogeniclineages.
Commonlyusedwithascorbicacidandβ-Glyforosteogenicdifferentiationofstemcells.
Alsoshowspotentanti-inflammatoryandimmunospressanteffects.Activeinvivo.
Watersolubledexamethasonealsoavailable.
- AlternativenamesDex
- BiologicalactionAgoNIST
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione
- MolecularWeight392.47
- Chemicalstructure
![Dexamethasone [50-02-2]](images/hellobio/201710/hb2521.png "Dexamethasone [50-02-2]")
- MolecularFormulaC22H29FO5
- CASNumber50-02-2
- PubChemidentifier5743
- SMILESC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C
- InChiInChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
- InChiKeyUREBDLICKHMUKA-CXSFZGCWSA-N
- MDLnumberMFCD00064136
StoringandUsingYourProduct
- Storageinstructions-20°C.Protectfromlight.
- SolubilityoverviewSolubleinDSMO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforDexamethasone
Dexamethasonealleviatestumor-associatedbraindamageandangiogenesis.
FanZetal(2014)PLoSOne9(4):e93264.PubMedID:24714627GlucocorticoidreceptorantagonismbycyproteroneacetateandRU486.
HonerCetal(2003)MolPharmacol63(5):1012-20.PubMedID:12695529Shortboutsofmechanicalloadingareaseffectiveasdexamethasoneatinducingmatrixproductionbyhumanbonemarrowmesenchymalstemcell.
SittichokechaiwutAetal(2010)EurCellMater20:45-57.PubMedID:20648425
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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