Hello Bio/DAMGO/HB2409/1mg
商品编号：
HB2409-1mg
品牌：
hellobio
市场价：
¥409.50
美元价：
315.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
Properties
- ChemicalnameH-Tyr-D-Ala-Gly-N(Me)Phe-Gly-ol
- MolecularWeight513.7
- MolecularFormulaC26H35N5O6
- CASNumber78123-71-4
- PubChemidentifier5462471
- SMILESC[C@H](C(=O)NCC(=O)N(C)[C@@H](CC1=CC=CC=C1)C(=O)NCCO)NC(=O)[C@H](CC2=CC=C(C=C2)O)N
- InChiInChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1
- InChiKeyHPZJMUBDEAMBFI-WTNAPCKOSA-N
- MDLnumberMFCD00133215
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- SolubilityoverviewSolubleinwater(4mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforDAMGO
Pharmacologicalcharacterizationoftheclonedkappa-,delta-,andmu-opioidreceptors.
Raynoretal(1994)MolPharmacol45(2):330-4PubMedID:8114680Theμ-opioidreceptoragonistDAMGOpresynapticallysuppressessolitarytract-evokedinputtoneuronsintherostralsolitarynucleus.
Boxwelletal(2013)JNeurophysiol109(11):2815-26PubMedID:23486207DAMGOinthecentralamygdalaalleviatestheaffectivedimensionofpaininaratmodelofinflammatoryhyperalgesia.
Zhangetal(2013)Neuroscience252:359-66PubMedID:23994597
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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