Hello Bio/Daidzein/HB2488/50mg
商品编号：
HB2488-50mg
品牌：
hellobio
市场价：
¥1111.50
美元价：
855.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameDaidzein
- ShortdescriptionEstrogenreceptors(ER)agoNIST.Phytoestrogen.
- BIOLOGicaldescriptionEstrogenreceptors(ER)agonist.Soyphytoestrogenandgenisteinanalog.AlsoshowsactivityatPPARs.Showsbothestrogenic/anti-estrogenicactivity,inducesapoptosisandanticancereffects.Activeinvivo.
- BiologicalactionAgonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- MolecularWeight254.24
- Chemicalstructure
![Daidzein [486-66-8]](images/hellobio/201710/hb2488.png "Daidzein [486-66-8]")
- MolecularFormulaC15H10O4
- CASNumber486-66-8
- PubChemidentifier5281708
- SMILESC1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O
- InChiInChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
- InChiKeyZQSIJRDFPHDXIC-UHFFFAOYSA-N
- MDLnumberMFCD00016954
StoringandUsingYourProduct
- Storageinstructions-20°C(desiccate)
- SolubilityoverviewSolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforDaidzein
Isoflavonemetabolitesandtheirinvitrodualfunctions:theycanactasanestrogenicagonistorantagonistdependingontheestrogenconcentration.
HwangCSetal(2006)JSteroidBiochemMolBiol101(4-5):246-53.PubMedID:16965913Daidzeininducedapoptosisviadown-regulationofBcl-2/BaxandtriggeringofthemitochondrialpathwayinBGC-823cells.
TangSetal(2013)CellBiochemBiophys65(2):197-202.PubMedID:22926545DaidzeincausescellcyclearrestattheG1andG2/MphasesinhumanbreastcancerMCF-7andMDA-MB-453cells.
ChoiEJetal(2008)Phytomedicine15(9):683-90.PubMedID:18541420
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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