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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > 你好Bio/CP 94253盐酸盐/HB1671/50mg
商品详细你好Bio/CP 94253盐酸盐/HB1671/50mg
你好Bio/CP 94253盐酸盐/HB1671/50mg
你好Bio/CP 94253盐酸盐/HB1671/50mg
商品编号: HB1671-50mg
品牌: hellobio
市场价: ¥6766.50
美元价: 5205.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Productoverview

  • Name
    CP94253hydrochloride
  • Shortdescription
    Potent,selective5-HT1BreceptoragoNIST
  • BIOLOGicaldescription
    Potent,selective5-HT1Breceptoragonist(Kivaluesare2,89,49,860,and1600nMat5-HT1B,5-HT1A,5-HT1D,5-HT1Cand5-HT2respectively).Reducesfootintake,anticonvulsantandantidepressant-likeeffects.Activeinvivo.Blood-brainbarrierpermeable.
  • Biologicalaction
    Agonist
  • Purity
    >98%
  • Ourproductsinaction
    SubmitYourCitationNow

Properties

  • Chemicalname
    5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridinehydrochloride
  • MolecularWeight
    293.8
  • Chemicalstructure
    CP 94253 hydrochloride [845861-39-4]
  • MolecularFormula
    C15H19N3O.HCl
  • CASNumber
    845861-39-4

StoringandUsingYourProduct

  • Storageinstructions
    roomtemperature(desiccate)
  • Important
    ThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.

ReferencesforCP94253hydrochloride

  • Effectof5-HT1Breceptoragonistsinjectedintotheprefrontalcortexonmaternalaggressioninrats.

    VeigaCPetal(2007)BrazJMedBiolRes40(6):825-30.
    PubMedID:17581682
  • Biochemicalandbehavioralstudiesofthe5-HT1Breceptoragonist,CP-94,253

    Koetetal(1992)Drugdevres26(3):241-250
  • Antidepressant-likeeffectoftheselective5-HT1BreceptoragonistCP94253:apossIBLemechanismofaction.

    TatarczyńskaEetal(2005)EurJPharmacol516(1):46-50.
    PubMedID:15913599
  • Anticonvulsanteffectoftheselective5-HT1BreceptoragonistCP94253inmice.

    WesołowskaAetal(2006)EurJPharmacol541(1-2):57-63.
    PubMedID:16765343
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632,  SB 431542 DAPT.