你好Bio/CP 94253盐酸盐/HB1671/10mg
商品编号：
HB1671-10mg
品牌：
hellobio
市场价：
¥1852.50
美元价：
1425.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product overview
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NameCP 94253 hydrochloride
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Short descriptionPotent, selective 5-HT1B receptor agonist
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Biological descriptionPotent, selective 5-HT1B receptor agonist (Ki values are 2, 89, 49, 860, and 1600 nM at 5-HT1B, 5-HT1A, 5-HT1D, 5-HT1C and 5-HT2 respectively). Reduces foot intake, anticonvulsant and antidepressant-like effects. Active in vivo. Blood-brain barrier permeable.
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Biological actionAgonist
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Purity>98%
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Our products in actionSubmit Your Citation Now
Properties
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Chemical name5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride
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Molecular Weight293.8
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Chemical structure
![CP 94253 hydrochloride [845861-39-4]](images/hellobio/201710/hb1671.png "CP 94253 hydrochloride [845861-39-4]")
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Molecular FormulaC15H19N3O.HCl
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CAS Number845861-39-4
Storing and Using Your Product
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Storage instructionsroom temperature (desiccate)
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ImportantThis product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.
References for CP 94253 hydrochloride
Effect of 5-HT1B receptor agonists injected into the prefrontal cortex on maternal aggression in rats.
Veiga CP et al (2007) Braz J Med Biol Res 40(6) : 825-30.PubMedID: 17581682Biochemical and behavioral studies of the 5-HT1B receptor agonist, CP-94,253
Koet et al (1992) Drug dev res 26(3) : 241-250Antidepressant-like effect of the selective 5-HT1B receptor agonist CP 94253: a possible mechanism of action.
Tatarczyńska E et al (2005) Eur J Pharmacol 516(1) : 46-50.PubMedID: 15913599Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.
Wesołowska A et al (2006) Eur J Pharmacol 541(1-2) : 57-63.PubMedID: 16765343
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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