Hello Bio/Corticosterone/HB2808/100mg
商品编号：
HB2808-100mg
品牌：
hellobio
市场价：
¥1033.50
美元价：
795.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCorticosterone
- ShortdescriptionEndogenousgluococorticoid.MRandGRagoNIST.
- BIOLOGicaldescriptionEndogenousgluococorticoid.Actsasamineralcorticoid(MR)andglucocorticoidreceptor(GR)agonist.Involvedinawiderangeofbiologicalprocessesandshowsavarietyofeffects.
- BiologicalactionAgonist
- Purity>99%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione
- MolecularWeight346.46
- Chemicalstructure
![Corticosterone [50-22-6]](images/hellobio/201710/hb2808.png "Corticosterone [50-22-6]")
- MolecularFormulaC21H30O4
- CASNumber50-22-6
- PubChemidentifier5753
- SMILESC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O
- InChiInChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
- InChiKeyOMFXVFTZEKFJBZ-HJTSIMOOSA-N
- MDLnumberMFCD00037715
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinDMSO(100mM)andinethanol(10mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCorticosterone
Hippocampalcorticosteroneimpairsmemoryconsolidationduringsleepbutimprovesconsolidationinthewakestate.
KelemenEetal(2014)Hippocampus24(5):510-5.PubMedID:24596244CorticosteronerapidlyincreasesthornsofCA3neuronsviasynaptic/extranuclearglucocorticoidreceptorinrathippocampus.
YoshiyaMetal(2013)FrontNeuralCircuits7:191PubMedID:24348341Corticosteroneactsinthenucleusaccumbenstoenhancedopaminesignalingandpotentiatereinstatementofcocaineseeking.
GrafENetal(2013)JNeurosci33(29):11800-10.PubMedID:23864669
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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