Hello Bio/Cinnabarinic acid/HB0195/50mg
商品编号：
HB0195-50mg
品牌：
hellobio
市场价：
¥9262.50
美元价：
7125.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameCinnabarinicacid
- ShortdescriptionSelectivemGlu4agoNIST
- BIOLOGicaldescriptionSelectivemGlu4receptoragonist.Endogenousmetaboliteofthekynureninepathway.ShowsnoactivityatothermGlureceptors.ProtectiveagainstEAE,amultiplesclerosismodelinmice.
- BiologicalactionAgonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname2-Amino-3-oxo-3H-phenoxazine-1,9-dicarboxylicacid
- MolecularWeight300.22
- Chemicalstructure
![Cinnabarinic acid [606-59-7]](images/hellobio/201710/hb0195.png "Cinnabarinic acid [606-59-7]")
- MolecularFormulaC14H8N2O6
- CASNumber606-59-7
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewsolubleinDMSO(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforCinnabarinicacid
Cinnabarinicacid,anendogenousmetaboliteofthekynureninepathway,activatestype4metabotropicglutamatereceptors.
FazioFetal(2012)MolPharmacol81(5):643-56.PubMedID:22311707Anexpandingrangeoftargetsforkynureninemetabolitesoftryptophan.
StoneTWetal(2013)TrendsPharmacolSci34(2):136-43.PubMedID:23123095Cinnabarinicacid,anendogenousagonistoftype-4metabotropicglutamatereceptor,suppressesexperimentalautoimmuneencephalomyelitisinmice.
FazioFetal(2014)Neuropharmacology81:237-43.PubMedID:24565643
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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