你好生物/（E）-辣椒素/HB1179/50mg
商品编号：
HB1179-50mg
品牌：
hellobio
市场价：
¥702.00
美元价：
540.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- Name(E)-Capsaicin
- ShortdescriptionTRPV1channelagoNIST
- BIOLOGicaldescriptionTRPV1channelagonist(pEC50valuesare7.10and7.97forhumanandratTRPV1respectively).Carbonicanhydraseinhibitor(Kivaluesare696.15and208.37µMforhCAIanhCAIIrespectively).AlsoCYP3AsubfamilyandP-gpinhibitor.Inducescellcyclearrest,apoptosisandinhibitsproliferationDisplaysapoptosisinducing,
- BiologicalactionAgonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(E)-N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide
- MolecularWeight305.42
- Chemicalstructure
![(E)-Capsaicin [404-86-4]](images/hellobio/201710/hb1179.png "(E)-Capsaicin [404-86-4]")
- MolecularFormulaC18H27NO3
- CASNumber404-86-4
- PubChemidentifier1548943
- SMILESCC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC
- InChiInChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
- InChiKeyYKPUWZUDDOIDPM-SOFGYWHQSA-N
- MDLnumberMFCD00017259
StoringandUsingYourProduct
- StorageinstructionsRoomtemperature
- SolubilityoverviewSolubleinDMSO(50mM)andinethanol(50mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(E)-Capsaicin
Capsaicin:apotentinhibitorofcarbonicanhydraseisoenzymes.
ArabaciBetal(2014)Molecules19(7):10103-14.PubMedID:25014536Transientreceptorpotentialtypevanilloid1suppressesskincarcinogenesis.
BodeAMetal(2009)CancerRes69(3):905-13.PubMedID:19155296Capsaicin:cellulartargets,mechanismsofaction,andselectivityforthinsensoryneurons.
HolzerP(1991)PharmacolRev43(2):143-201.PubMedID:1852779Sensoryneuron-specificactionsofcapsaicin:mechanismsandapplications.
BevanSetal(1990)TrendsPharmacolSci11(8):330-3.PubMedID:2203194
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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