Hello Bio/(-)-Cannabidiol/HB2785/50mg
商品编号:
HB2785-50mg
品牌:
hellobio
市场价:
¥4446.00
美元价:
3420.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Productoverview
- Name(-)-CannABIdiol
- ShortdescriptionNonpsychoactivecannabinoidfoundincannabis
- BIOLOGicaldescriptionNonpsychoactivecannabinoidfoundincannabis.DemonstrateslowaffinityforCB1andCB2receptors(Kivaluesare4.35and2.86μMrespectively).AlsoactsasaGPR55antagoNIST.Showsanxiolytic,antipsychotic,antidepressantandneuroprotectiveproperties.Activeinvivo,
- AlternativenamesCBD
- BiologicalactionAgonist
- Purity>98%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol
- MolecularWeight314.47
- Chemicalstructure
- MolecularFormulaC21H30O2
- CASNumber13956-29-1
- PubChemidentifier644019
- SMILESCCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O
- InChiInChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1
- InChiKeyQHMBSVQNZZTUGM-ZWKOTPCHSA-N
- MDLnumberMFCD00869597
StoringandUsingYourProduct
- Storageinstructions-20°C
- SolubilityoverviewSolubleinethanol(75mM)andinDMSO(75mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
Referencesfor(-)-Cannabidiol
ThediverseCB1andCB2receptorpharmacologyofthreeplantcannabinoids:delta9-tetrahydrocannabinol,cannabidiolanddelta9-tetrahydrocannabivarin.
Pertwee(2008)BrJPharmacol153(2):199-215PubMedID:17828291Type1cannabinoidreceptorligandsdisplayfunctionalselectivityinacellculturemodelofstriatalmediumspinyprojectionneurons.
Laprairieetal(2014)JBiolChem289(36):24845-62PubMedID:25037227TheorphanreceptorGPR55isanovelcannabinoidreceptor.
Rybergetal(2007)BrJPharmacol152(7):1092-101.PubMedID:17876302
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%。热销产品线:酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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