Hello Bio/Allopregnanolone/HB0932/50mg
商品编号：
HB0932-50mg
品牌：
hellobio
市场价：
¥7741.50
美元价：
5955.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameAllopregnanolone
- ShortdescriptionPotentGABAAreceptorpositiveallostericmodulator
- BIOLOGicaldescriptionPotentGABAAreceptorpositiveallostericmodulator.Endogenousneurosteroid;showssedative,anticonvulsive,antidepressantandanxiolyticactions.ShowsneurogeniceffectsinAlzheimer"sdiseaseandParkinson"sdisease.
- BiologicalactionPAM
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname(3α,5α)-3-Hydroxy-pregnan-20-one
- MolecularWeight318.49
- Chemicalstructure
![Allopregnanolone [516-54-1]](images/hellobio/201710/hb0932.png "Allopregnanolone [516-54-1]")
- MolecularFormulaC21H34O2
- CASNumber516-54-1
StoringandUsingYourProduct
- Storageinstructionsroomtemperature
- SolubilityoverviewsolubleinDMSO(100mM)orethanol(100mM)
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforAllopregnanolone
Neurosteroids:endogenousroleinthehumanbrainandtherapeuticpotentials.
ReddyDS(2010)ProgBrainRes186:113-37.PubMedID:21094889NeurosteroidsactonrecombinanthumanGABAAreceptors.
PuiaGetal(1990)Neuron4(5):759-65.PubMedID:2160838AllopregnanolonereinstatestyrosinehydroxylaseimmunoreactiveneuronsandmotorperformanceinanMPTP-lesionedmousemodelofParkinson"sdisease.
AdeosunSOetal(2012)PLoSOne7(11):e50040.PubMedID:23209637
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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