你好Bio/Indo-1 AM/HB0790/1mg
市场价：
¥3256.50
美元价：
2505.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Productoverview
- NameIndo-1AM
- ShortdescriptionCalciumsensitivefluorescentdye
- AlternativenamesIndo-1/AM;Indo-1acetoxymethylester
- BIOLOGicaldescriptionCellpermeablecalciumsensitiveflouresecentdye.BindstoCa2+(Kd=0.25µM).RatiometricandexcitedbyUVlight.HydrolysedintoIndo-1bycytoplasmicesterases.MaybeusedformonitoringCa<2+>levels.Inhibitsrenalproximaltubulecellvolumeregulation.
- BiologicalactionDyes&stains
- Purity>95%
- OurproductsinactionSubmitYourCitationNow
Properties
- Chemicalname1-[2-Amino-5-(6-carboxyindol-2-yl)phenoxy]-2-(2"-amino-5"-methylphenoxy)ethane-N,N,N",N"-tetraaceticacid,pentaacetoxymethylester
- MolecularWeight1009.9
- Chemicalstructure
![Indo-1 AM [112926-02-0]](images/hellobio/201710/hb0790.png "Indo-1 AM [112926-02-0]")
- MolecularFormulaC47H51N3O22
- CASNumber112926-02-0
StoringandUsingYourProduct
- Storageinstructions-20°C
- ImportantThisproductisforRESEARCHUSEONLYandisnotintendedfortherapeuticordiagnosticuse.Notforhumanorveterinaryuse.
ReferencesforIndo-1AM
Thefluorescentcalciumindicatorindo-1/AMinhibitsrenalproximaltubulecellvolumeregulation.
KanliHetal(1992)AnnClinLabSci22(4):236-44.PubMedID:1503391Thesourceofepifluorescenceinisolatedperfusedheartloadedwithfura2-AMorindo1-AM.
ShinozakiTetal(1993)HeartVessels8(2):79-84.PubMedID:8314741Calciummobilizationinhumanplateletsusingindo-1andflowcytometry.
JenningsLKetal(1989)Blood74(8):2674-80.PubMedID:2510834AnewgenerationofCa2+indicatorswithgreatlyimprovedfluorescenceproperties.
GrynkiewiczGetal(1985)JBiolChem260(6):3440-50.PubMedID:3838314
品牌介绍
Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业，总部位于英国布里斯托尔，在美国普林斯顿设有分公司，主旨在于提供质优价廉的生命科学研究工具，主要产品线为小分子化合物，如激动剂、拮抗剂、抑制剂等，部分产品价格甚至低至其他供应商的50%。热销产品线：酶抑制剂和激动剂ROCK inhibitor Y-27632, PKA inhibitor KT 5720 , adenylyl cyclase activator Forskolin, and novel GRK2/3 inhibitor Cmpd101等。 离子通道调节剂NMDA antagonist D-AP5, sodium channel blocker tetrodotoxin citrate, TRP antagonist capsazepine, and GABAA antagonist SR 95531 等。信号通路工具各种信号通路抑制剂、激动剂表观遗传学研究工具potent HDAC inhibitor Trichostatin A, DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine,BET bromodomain inhibitor (+)-JQ1 and potent,selective GLP / G9a HMTase inhibitor BIX 01294 等受体配体novel selective GRK2/3 inhibitor, NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.等干细胞调节剂ROCK inhibitor Y-27632, SB 431542 DAPT.
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